 यहाँ ब्रकिल करध्ट्टीरा रए करेब जाएंग्गा क्या व penalties मालिकुल करेट्टीर करने लग्टीर करूग। करेबट्टीर जाएंग्टीर रए करने आई बालिखीन ब्रकिल यहाँ क्रब्साइकल के अंदर वो सिट्रिके सेद है। और इसके लावा जो हमपोट्रन चीस हमने पडिया वो यह क्रब्साइकल में 3 NADH बनते है। और 1 FADH 2 बनता है। अब हम यह साइकल को दीटेल में देखते हैं क्यों कोट से स्टेप्स हैं गौलु को असे आंद पर के बन क्या बन के है। प्प्रूबेट बन लेए। क्रब्साइकल में आंद प्रड्व्ट नहीं है बलके जो छीज़े बन दीख हो दोबारा फिर रीषाइकल हो रीएं रीषाइकल हो तो जाए अरहीं अब दब खुछ कुछ कुछ लें में ब्यी प्रट्रच्ट द्यों से लींगा के भो रही हैं जो क्यक आगय खुछ वर्च्ट द्यों से लिए हैं here we have the complete cycle of tri-carboxylic cycle or the crab cycle which we have we will start with acetyl-coenzyme A acetyl-coenzyme A basically was made from pyruvate degradation when pyruvate, glycolysis was made from pyruvate in mytochondria when pyruvate further break down then acetyl-coenzyme A was made from pyruvate acetyl-coenzyme A will react with oxaloacetic acid all these things are in mytochondria so this reaction will be in mytochondria so in this reaction, if you consider oxaloacetic acid is a 4-carbon molecule when acetyl-coenzyme is a 2-carbon it will combine with citric acid which is a 6-carbon molecule it will be citric acid citric acid is in a simple way citric acid makes its own isopharm which is called isocitrate isocitric acid converts into alpha-ketoglutarate if we look at alpha-ketoglutarate one molecule of carbon dioxide is released here and one molecule of NADH is formed here this means that one of the 6-carbon molecules is formed in carbon dioxide now we have these 5-carbon molecules that is alpha-ketoglutarate along with NADH if NADH is formed then high energy electrons are harvested here from citric acid molecule next step alpha-ketoglutarate is converted into succinic acid succinic acid is sometimes called succinate this is also an intermediate step in which succinyl-coenzyme A is formed and then it goes on to the next step if we look at alpha-ketoglutarate which is used in both the words you can use alpha-ketoglutarate acid and you can use alpha-ketoglutarate there will be de-carboxylation in this one more carbon dioxide form will be released here and this succinate acid will form 4-carbon molecule if we look at this step if we look at the 2-carbon molecules that were formed from the glucose in one form it is formed on this step and when the second carbon is formed here this means that the carbon skeleton that is formed here is completely degraded all the carbon skeleton is converted into carbon dioxide this step is formed by one molecule of NADH NADH is formed and one molecule of GTP is formed this is basically equivalent to ATP this ATP is used in the cell or GTP as GTP is used in the cell this is the only energy molecule that is formed in the crab cycle anywhere else in the crab cycle you cannot see the molecule of ATP just NADH and FADH2 are formed this is the second NADH then succinate acid is converted into these are the different steps here it is formed by fumaric acid further it is formed by auxiliary acid these are further steps FADH2 is formed on the first step and NADH2 is formed on the next step FADH2 and NADH if we look at the total there are one, two, three three NADH molecules are synthesized one second molecule and the third molecule so three molecules of NADH are synthesized here and one molecule of FADH2 if we look at the overall in the crab cycle we see three NADH molecules one FADH2 molecule is formed and one molecule of GTP is formed by the end of this side again we have the same auxiliary acid from where we started because of this cycle we call it crab cycle this is the pathway which is called a cycle so what is the overall reaction of crab cycle if we try to sum up the overall reaction of crab cycle the acetyl unit is entered acetyl coenzyme A is formed acetyl coenzyme A is entered three NADH molecules are used and one molecule of FAD one molecule of ADP and one inorganic phosphate is used what is the output acetyl unit had two carbons they will be released in the form of two carbons so we will write 2 CO2 in the acetyl group they are converted in the carbons three NAD is converted to three NADH FAD is converted into FADH2 and ADP and inorganic phosphate will be made and GTP will be synthesized so this is the overall reaction of crab cycle if we try to sum it up but crab cycle NADH and FADH2 production because at an average one at NADH molecule will produce three ATP molecules so if there are three NADH in one crab cycle then three multiplat by three nine ATP molecules are to be formed and one FADH2 will give approximately two ATP molecules so it means nine ATPs and two nine ATPs will come from NADH and two ATPs will come from FADH2