 Abstract Fabry disease, FD, is a progressive X-linked inherited disorder of glycosfingolipid metabolism due to deficient or absent lysosomal galactosidase activity. The disease affects both males and females, with males being more severely affected. FD can cause neurological, cutaneous, renal, cardiovascular, cochleovestibular, and cerebrovascular symptoms. Diagnosis is typically done through enzyme analysis or genetic testing. Treatment options include enzyme replacement therapy, pain relief with analgesic drugs, nephroprotection, and antyrhythmic agents. While there is evidence that long-term enzyme therapy can halt disease progression, adjunctive therapies are also important. Oral therapy is being researched as a potential treatment option. This article was authored by German Dominik P. We are article.tv, links in the description below.