 A 59-year-old female received a living non-related kidney transplant while on bilatisept therapy. She subsequently developed fever, clinical wasting and a mediastinal mass. A mediastinal node biopsy revealed the presence of histoplasma capsulatum. The infection was successfully treated with appropriate antifungal medications. This is the first reported case of histoplasma capsulatum in a kidney transplanted patient on bilatisept therapy. This article was authored by Ernan Tramarki, Tatiana Rangel, Jose Andrews, and others.