 Hello everyone, I am Dr Bhava Adant, second year resident from Dr Deva Patil Medical College and Research Centre, Pune, here to present on the topic evaluation of congenital brain anomalies MRI series under the guidance of Professor Dr Tushar Karakasar. So introduction, the congenital brain defects are abnormalities in the brain that are present at the birth. The defect typically affects the bone and the soft tissue in the head and the spine. More than 2000 different congenital malformations of the brain have been described in the literature and the incidence is reported to be about 1% of all the live births. MRI is very useful in starting these malformations. So the incidence there is 2 to 3% of the incidence in the newborn which increases to 4 to 6% by the age of 5 years, 40 to 60% of all the birth defects are usually unknown, that cause is unknown. The genetic and chromosomal causes contribute to about 10 to 15% environmental causes contribute to 10% and other multifactorial causes contribute to 20 to 25%. So the aim and objective of this study is to study the MRI findings of the congenital brain anomalies, a simplified classification of the congenital anomalies affecting the brain followed by the images and the imaging finding of the common and certain interesting or important congenital anomalies of the brain. The study was done on 15 patients in a time span of 6 months who presented to us with complaints of seizures, developmental delay, weakness, learning disabilities, impaired coordination, vomiting and irritability. MRI was performed by 1.5 Tesla, Phillips Achiever. So in this table as we can see that there are specific anomalies and the timing at which it can be detected. In the doysil induction there is chari malformation which is detected by 4 weeks of the gestation and cephalosales are detected by 5 to 6 weeks of the gestation. Poloproencephaly in mental induction there are 3 diseases, poloproencephaly which is detected at 5 to 6 weeks of the gestation. Scepto-optic dysplasia is detected by 6 to 7 gestational weeks. Dandymocomal formation is detected by 7 to 10 gestational weeks. In neural proliferation and histogenesis there are 3 diseases, neurofibromitosis which is detected by 5 weeks to 6 months of the gestation. Tuberous sclerosis is also detected by 5 weeks to 6 months of the gestation. And primary hydrancephaly is detected by 3 months or later in life. In under migration there are 4 diseases. Scheisencephaly which is detected by 2 months of the gestation. Aguairi and pachyguairi are detected by 3 months of the gestation. Green matter heterotropias are detected by 5 months of the gestation. And dysgenesis of the corpus callosum is detected by 2 to 5 months of the gestation. So complete corpus callosul A genesis with colpocephaly. So these are the sagittal T2 weighted and axial T2 weighted images in which we can see that both the ventricles are separated with the dilated tricon and the occipital horn of the lateral ventricle with complete absence of the corpus callosul. So these are the, in unilaterally open lip Scheisencephaly we can, these are T1 and T2 axial weighted images in which we can see a well defined triangular cystic lesion which is extending from the margin of the body of the left lateral ventricle to the cortex having a density of the CSF which is hyper intense on T1 weighted images and hyper intense on T2 weighted images. In incomplete leisencephaly these are the axial coronal and sagittal images in which we can see that there are areas of patchy and egg area mainly in the perito occipital lobe pylaterally and shallow selcai are noted in the frontal lobes pylaterally. In unilaterally malformations these are the T2 weighted sagittal and coronal images in which we can see that there is tonsillar herniation and syringohydromyalia in the upper cervical region findings are consistent with unilaterally malformation. So this is a variant of the dandy vocal malformation in which we can see a well defined cystic lesion in the posterior posa in the midline which is hyper intense on T1 weighted images and hyper intense on T2 weighted images. They are dilated both lateral ventricles with very little cerebral parenchyma which appears thinned out. The third ventricle is not seen separately which is compressed by the posterior posa cyst. Gourmice of the cerebellum appears absent, tegmentum is not elevated and the posterior posa midline cyst is causing aqueductal stenosis and hydrincipin. So the conclusion of my study is MRI provides a detailed multiflanar imaging and exquisite contrast differentiation which is essential for classification and determination of the congenital malformations of the brain. Knowledge of normal brain development is essential for correctly identifying the abnormalities. The classification of congenital malformations continually changing the new insights into the brain development as the genetics of the congenital malformation become more complex MRI can provide important information on specific brain phenotypes. These are the references which I took for my study. Thank you.