 The study compares the effects of topical human amniotic membrane mesenchymal stem cell conditioned medium, HMMCCM, alone and with vitamin C and E on healing of chronic plantar ulcers in leprosy, CPUL. The results show that HMMCCM plus vitamin E is best for wound healing, with a mean difference in ulcer size being highest in this group. There were no side effects or complications. This article was authored by C.R.S. Prakoswa, F. Anatalia, D. Haninja, and others.