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Published on Oct 5, 2011
Children with CF have an abnormality in the function of a cell protein called the cystic fibrosis transmembrane conductance regulator (CFTR). CFTR controls the flow of water and certain salts in and out of the body's cells. As the movement of salt and water in and out of cells is altered, secretions become thickened. The thickened secretions can affect many organs and body systems.