 CD133-plus cells are mesenchymal stem cells derived from bone marrow mononuclear cells. These cells have been shown to possess high levels of CD34 expression, which allows them to differentiate into adherent cells. Furthermore, they have been found to secrete a variety of cytokines, including cardiac hypertrophic factor, pro-angiogenic factors, pro-inflammatory factors, wound healing factors, neurophilic factors, morphogenetic proteins, and hematopoietic growth factors. This suggests that CD133-plus cells may hold great potential for use in regenerative medicine applications.