 This study examined the prevalence of multidrug resistant Pseudomonas originosa in five hospitals in Qatar over a three-year period. The study found that the prevalence of multidrug resistant Pseudomonas originosa was 5.9%, which was lower than expected. Additionally, the study identified five dominant clones of Pseudomonas originosa, two of which were associated with higher mortality rates. This study provides valuable insight into the prevalence of multidrug resistant Pseudomonas originosa in Qatar and its association with certain strains and mortality rates. This article was authored by Masin A. Sid Ahmed, Hamid Abdel Hadi, Suleiman Abu Jaria and others.