 In this study, pomegranate flower extract, PFE, was found to be effective in reducing the renal toxicity caused by chemotherapy drug Cisplatin, CP. The low dose of PFE was able to reduce the serum level of creatinine and decrease the kidney weight, which suggests that PFE may have a protective effect against CP-induced renal toxicity. Additionally, PFE was found to increase the level of nitric oxide in the kidney, suggesting that PFE may help to reduce the oxidative stress caused by CP. This article was authored by Fatemay Matamati, Mehdi Nemepaksh, Ramesh Manajimi, and others.