 Semiconductor mode-locked lasers, MLLs, can provide coherent optical frequency combs, OFCs, with high repetition rates and output power, which have been recognized as potential multi-wavelength sources used in optical communication field due to their compactness, high efficiency, and low-cost properties. In this article, we have reviewed recent development of semiconductor MLL-based frequency comb generation. Different approaches of semiconductor MLLs for OFC generation are synoptically summarized based on various material platforms. The representative progress of 3V semiconductor MLLs on 3V platform and especially on C substrates is both discussed for the applications in integrated silicon photonics. This article is authored by Wei Wenqi, Chen Jiejin, Huang Jingxi, and others.