 This study aimed to identify predictive factors for intraoperative additional resection, IAR, and evaluate IAR repetition numbers in soft tissue for surgically treated oral squamous cell carcinoma, OSCC. The results showed that only postoperatively available PT status was a predictive factor for IAR, highlighting the importance of improving preoperative or intraoperative tumor visualization to avoid IAR. This article was authored by Mark Ooms, Lisa Ponke, Philip Wynand, and others.