 In this study, it was found that therapeutic penetrating keratoplasty, TPK, performed after anti-pythium therapy, APT, consisting of line solid and azithromycin had good anatomical outcomes. Additionally, a smaller graft size of less than 10 millimetres was associated with the higher chance of graft survival. This article was authored by Anahita Kate, Umar Thigley, Lakshmi Prasanna Ponnapti, and others.