 This study evaluated for different methods of registering computed tomography, CT, scans taken during microwave ablation, MWA, of normal liver tissue in an in vivo porcine model. The first two methods involved rigid registration, while the third and fourth involved elastic registration. The results showed that the best method for reducing interscan motion artifacts was a combination of both rigid and elastic registration. This combination resulted in a decrease in the distance traveled by the ablation probe, indicating less motion artifacts than when no registration was done at all. This article was authored by Bogdan Kosturko, Kirsten Robarth, Christian Althoff, and others.