 Good morning everyone. Myself Benita Singh Paria, resident at department of data diagnosis of Iman Singh medical college at Rajasthan. I'm very thankful to MRA teaching course for giving me this wonderful opportunity to present my paper and here I begin. The title of my study is to study MR imaging spectrum of orbital masses using DWA ADC as a power tool to differentiate malignant and benign masses. Introduction. Orbital and intraocular masses are relatively uncommon compared to other mass regions of the body. Orbital masses comprise of heterogeneous group of disorders including inflammatory benign malignant metastases, in which at times differentiating benign and malignant orbital lesion is difficult due to overlapping clinical presentation. MRA is modality of choice. CT is helpful in cases of suspected bony pathologies and calcifications. Advanced MRI techniques like diffusion weighted imaging with quantitative aprin diffusion coefficient mapping, provide additional information about the orbital masses based on the diffusability of water and tissue. DWA exploits the fact that movement of water is normally restricted in malignant tumors. DWA can be helpful noninvasive technique to differentiate between benign and malignant orbital masses based on aprin diffusion coefficient values. Objective to evaluate role of MRI in characterization for orbital masses to distinguish benign and malignant masses using DWA with ADC mapping. Materials and methods based with donor suspected orbital space or pan lesion presenting with ophthalmological complaints such as preproses, visual impairment, when during the study, study area was department radio diagnosis, department of telemology, 7 months in medical college at Boracistan, study table was quantitative, designers analytical type of observation study duration was that of 1 year, and equipment use was 3 Tesla MRA Phillips engineer machine. Techniques of following MRI protocol are followed. All cases were evaluated by DWI in exit links, the DDC map, single shot eco planner DWI sequence was done, DWI has obtained the diffusion weighted factor using B value 0500 and 1000 second per millimeter square. Region of interest analysis was performed by using measurements of areas of abnormality, seen on the mentioned MRA sequences and adjusted according to the size of the region. To achieve standardized condition for result analysis and avoid data contamination from edges and structure, RIR was placed within the area of solid region of preferred care was taken to avoid the edges to extend the effect of partial volumetric region. Results, 40s and patients suspected orbital mass evaluated using Contas and Anne's MRI with DWI DC after taking relevant clinical history. Amongst 47 analyzed patient, 24 were malignant, rest 23 were benign. Histopathological examination clinical follow-up were done to reach the final diagnosis. Male to female ratio is 1.2 is 2.1. Most common age group involved was 30 to 40 years, mean age of presentation was 34 years, common symptom of presentation was initial impairment, predominantly reduced patient followed by proprosy. 88% malignant lesion showed diffusion restriction, 78% benign lesion, diffusion restriction was absent. The mean ADC and malignant lesion was 0.67 into 10 to the minus 3 and benign lesion was 1.251 into 10 to the minus 3 millimeter square per second. The difference in mean ADC or malignant benign lesion was statistically significant. Our OSEC curve analysis revealed ADC value of 0.85 into 10 to the minus 3 has cut off for differentiation of malignant benign lesions, the sensitivity being 80% and specific to being 80%. Retinodostoma had lowest ADC value in malignant lesion and Infantinoma had highest ADC in benign lesions. Limitation were few of inflammatory lesion forming orbital cellulitis due to presence of purulent content showed diffusion restriction with low ADC mean 0.557 amongst benign lesions. This table includes all the malignant orbital masses included in my study with the mean ADC values, lowest being that of retinoblastoma. This table is the list of all the benign orbital masses included in my study with the mean ADC values, highest being that of Nymphenzoa. This is the bar graph showing the mean ADC of malignant benign orbital masses. This is the compartmental distribution of orbital masses into intra-conal and conal, extroconal and multi-compartmental. Now discussion, malignant lesion of low ADC as compared to benign lesion which is attributed to the fact that malignant lesions are hypersimilar with enlarged nuclei having increased nucleus to cyclopolisment ratio. This histological nature reduces available space for water proton diffusion in both intra and extrocellular spaces so result in decreased ADC values. In our study taking ADC value of 0.85 into 10 to the minus 3 millimeters per second as threshold to differentiate malignant benign lesion has sensitivity of 80%. And specificity of 80%. Addition of DWI has led to increased accuracy of MR in characterizing indeterminate lesion which would further help in patient management so that either early intervention or initial conservative treatment would be undertaken. Now I'll be showing few of my cases starting with case 1, a 35 year female present with complaints of significant reduced lesion. Agile T1 weighted shows a hyper intense intraocular mass which is hypo intense on Agile T2 images showing diffusion restriction, showing that corresponding fallen ADC of mean ADC values of 0.617 into 10 to the minus 3. This lesion came out to be ocular melanoma, fallen ADC corresponds to the malignant orbital mass. Case 2, a 34 year female present with complaints of proptosis reduced vision reclamation. Agile MR sequence shows a well-defined extroconium mass which is iso intense to muscle on T1, hyper intense on T2, showing increased diffusion with increased ADC, high signal intensity on ADC with ADC value of 1.61 into 10 to the minus 3. It was a case of melanoma and a benign lesion. Case 3, of a 1 year old child present with proptosis of right eye. Agile MR sequence shows fusiform enlargement of the right optic nerve which is iso intense on T1, hyper intense on T2, showing increased diffusability and high ADC value mean being 1.8 at the lesion mass optic nerve Lyoma. Case 4, a 66 year female present with reduced vision and palpibril, lateral orbit is swelling. Agile MR sequences show diffused enlargement of right tachymil gland in the right superior orbital orbit, which is iso intense both on T1 and T2, shows intense contrast enhancement. Diffusion restriction is present with fallen ADC mean being 0.667 into 10 to the minus 3. It was a case of lymphoma. Case 5, a 4 year old boy present with lipoporia T2 weighted axial and sagittal images showed a circumscribed retinal mass which is hypo intense on T2, showing intense contrast enhancement, showing diffusion restriction with corresponding fallen ADC, the mean ADC value mean 0.491 into 10 to the minus 3. It was a case of retinoblastoma. Case 6, a 2 year old child with known case of B cell leukemia present with complaints of bilateral temporal swelling. MR is revealed by lateral symmetrical soft tissue masses on lateral orbital involving the lateral wall of the orbit causing erosion of underlying bones. The lesion was iso intense on T1 and that on T2, showing diffusion restriction fallen ADC of 0.622 into 10 to the minus 3. These were a case of leukemia. The conclusion of my study is contrast in MR is extreme imaging modality for vital lesion due to superior soft tissue contrast, proper delineation of vital compartment and abicting the extent of lesion. By analyzing, we have already observed that there is significant difference in ADC values of benign and medicated or vital masses. Hence, we conclude that TWA with ADC values are additional MRI sequences, which can be valuable noninvasive tools to predict malignancy and help to guide and to help guide appropriate management. Thank you for your time.