 The novel coronavirus, SARS-CoV-2, has caused a global pandemic due to its rapid spread and high mortality rate. It is important to develop rapid diagnostic tools to identify infected individuals and contain the spread of the virus. Several molecular biology techniques such as PCR, LAMP, and LFA have been used to detect SARS-CoV-2, but they require specialized equipment and trained personnel, making them impractical for use in resource-limited settings. In order to address this issue, researchers have developed several alternative methods based on sensors and biosensors, including optical sensors, electrochemical sensors, and apto sensors. These methods offer the potential to rapidly diagnose SARS-CoV-2 infections without requiring specialized equipment or trained personnel. This article was authored by Yassin Orgy, Hesse Maden-Sarabi, Neema Hemmat, and others.