 Importance play a key role in the transport of proteins from the cytoplasm to the nucleus. In this study, researchers found that certain importance can bind to nascent protein chains before they reach the nucleus, potentially helping to prevent them from aggregating. The findings suggest that the nuclear import system is closely linked to the folding and chaperoning of nascent protein chains. This article was authored by Maximilian Seidel, Natali Romanov, Agnieszka Abaska-Kosinska, and others.