 Hello, I am Dr. Piyush Bajpayee, I am a medical hematologist at Manipal Hospital, Dwarka, New Delhi. Today we will be talking about multiple myeloma. So multiple myeloma is basically a hematological malignancy of plasma cell, which are found basically in the blood and are produced in the bone marrow to be specific. So, plasma cell is a type of white blood cell, WBC, which works in our antibody production. And if this sometimes becomes a cancerous, it is called multiple myeloma. So, in multiple myeloma, basically the crab symptoms, which we call them, they sometimes predominate symptoms. And if we talk about crab symptoms, hypercalcemia, that is, the increase of calcium levels, renal dysfunction, kidney dysfunction, bone symptoms, that is, the lower back pain or any bone pain, that could be the starting point of myeloma. Again, anemia is one thing which in the crab criteria, which should be observed that if there is anemia and there is an iron deficiency or iron supplementation, there is no correction of anemia. So, it could be multiple myeloma. The age group is usually above the age of 40 years that multiple myeloma is found. If we talk about the treatment of multiple myeloma, the use of chemotherapy is often less. And the use of targeted therapy and modulation therapy, plasma modulation therapy is more. So, there is an induction therapy of about 4 to 6 months and there is a role of autologous bone marrow transplant. Autologous bone marrow transplant, if we talk about it, there are two types of bone marrow transplant. One is autologous and allogenic. In autologous, the stem cells of the patient or the progenitor cells are taken. We store them and then give high dose chemotherapy to end myeloma cells. After that, the patient's own blood is used again. This is in a very aseptic precautions. It is in a specific room, which we call bone marrow transplant room. And for this, there are specialized nurses who care during the course of state. After this, patients can spend a good life and a good life. Thank you.