 Staphylococcus aureus is a dangerous pathogen that causes severe systemic infections and is highly resistant to many antibiotics. Despite the lack of new antibiotics developed over the past few decades, researchers have been working on various strategies to fight off S. These include targeting specific genes or proteins involved in the bacteria's survival mechanisms, developing vaccines, and using existing drugs in combination with other compounds. This article was authored by Edward J.A. Douglas, Sri W. Willandari, Scott D. Lovell and others.