 Telemedicine, telehealth, and e-health are three emerging technologies that have been shown to be effective in managing chronic pain. These technologies provide patients with access to medical professionals from remote locations, allowing them to receive treatment without having to travel to a physical location. Additionally, multi-agent systems, MAS, can be used to facilitate communication between multiple agents, such as doctors and nurses, to help manage complex cases. The use of these technologies has been shown to improve patient outcomes and reduce costs associated with traditional face-to-face treatments. However, there is still much work to be done in order to fully understand how best to implement these technologies in clinical settings. This article was authored by Manna Ahmed Kamal, Zaynab Ismail, Islam Muhammad Shihada, and others.