 This article investigates entropy generation on MHD-Cas and nanofluid over a porous stretching slash shrinking surface while considering nonlinear thermal radiation and chemical reaction. The governing flow problem involves momentum, energy, and nanoparticle concentration equations, which are transformed into ordinary differential equations using similarity transformation variables. These highly nonlinear coupled ordinary differential equations are solved numerically using the successive linearization method, SLM, and Chibushev spectral collocation method. The study discusses the impacts of various parameters on velocity, temperature, concentration, and entropy profiles and analyzes the local Nusselt and Sherwood numbers with tables. A comparison with existing studies is also made. This article was authored by Jiaqing, Mohamed Mubashir Bhatti, Munawar Ali Abbas, and others.