 The essential oil from Lipia-Originoid's thymolcarbocrawl-2 chemotype, LOC-2, has shown potential for use as a natural antibacterial agent. It has been found to decrease the expression of genes involved in motility, adherence and cellular aggregation, exopolysaccharide production, quorum sensing and biofilm formation in E. Additionally, it has been found to positively regulate the expression of genes encoding inhibitors of biofilm formation, suggesting its potential as a natural antibacterial alternative to conventional antibiotics. This article was authored by Andres Martinez, Elena Esteschenko, Rodrigo Torres says, and others.