 Exosomes are small membrane vesicles that are released from cells into bodily fluids such as plasma, urine, saliva, and amniotic fluid. These vesicles contain proteins, myrnas, and mRNAs which can be used as a platform for diagnosis. We have developed a method to isolate these vesicles from bodily fluids allowing us to extract their contents for further analysis. This includes identifying protein markers extracting RNA and using it to type for genetic variations. Our results show that exosomes from bodily fluids can be used to identify genetic variations such as the CD-24 single nucleotide polymorphism, SNP, which can be used to determine the sex of a fetus. Additionally, we have shown that exosomes can protect RNA from degradation, making them ideal candidates for use in diagnostic tests. This article was authored by Janssen Johannes W. G., Watt and Kathleen, writing the Johannes and others.