 Hello everyone, welcome back to another session in dentistry and more today's topic is adenoide cystic carcinoma which is the most common neoplasma of submanipular and sublingual gland. So which is also known as cylindroma adenocystic carcinoma or adenocystic basal silk carcinoma. So let's get into details of adenoide cystic carcinoma. So adenoide cystic carcinoma which is a slow growing but aggressive neoplasm with remarkable capacity to recur and profound tendency to invade perineural lymphatic spaces, okay. So this is as I told most common neoplasm of submanipular and sublingual salivary glands and also it is seen in minor salivary glands in the palate. So 50 to 70 percentage of this seen in minor salivary glands the palate is the most common site and it is a third most common malignant neoplasm seen in the salivary gland after mucoepidermoid carcinoma and polymorphous adenocarcinoma. So this is the third most common malignant neoplasm of salivary gland and the most common neoplasm of submanipular and sublingual gland and it is most commonly seen between fifth to seventh decade. Actually there is no gender predilection for this disease this neoplasm and there is a slight female predilection as reported. So in clinical presentation the pain is a common and important finding it is a slow growing mass. Patients often complains of a constant low grade dull ache which gradually increases in intensity. Facial nerve paralysis may develop with parotid tumors. Palatal tumors can be very smooth surface or maybe even ulcerated. Tumors arising in the palate or maxillary soiness it may show radiographic evidence of bone destruction so it may involve the bone maxillary bone and it will distract it. So while moving on to the histopathologic features the adenocarcinoma is basically composed of mixture of myoepithelial cell and ductile like cells that can have a varied arrangement. So there are three basic patterns of the disease that is cribriform type, tubular type and solid type. So cribriform type which is well differentiated and tubular type is moderately differentiated and solid type is undifferentiated type. So you can make out from the picture it is well differentiated moderately differentiated and undifferentiated. So usually a combination at these is seen on the tumories classified based on the predominant pattern. So whichever pattern is seen in the histopathology section. So we will categorize this adenocarcinoma. This is the most classic and best recognized appearance which is characterized by islands of basilar epithelial cells that contain multiple cylindrical cyst-like spaces which is resembling Swiss cheese or honeycomb pattern. So in adenocarcinoma the cribriform type shows Swiss cheese or honeycomb pattern. So this might be asked as a short note Swiss cheese or honeycomb. It is not just seen in adenocarcinoma there are few others in your plasm also. The same pattern is seen. So these spaces often contain a mildly basophilic mucoid material and a hyalinized isonophilic product or a compound mucoid hyalinized appearance is seen. So sometimes the hyalinized material also surround these cribriform hyalins. So it is like a Swiss cheese honeycomb pattern with hyalinized areas. So whereas tubular pattern these are tubular structures that are lined by stratified cuboidal epithelium. So it is lined by stratified cuboidal epithelium. So in the longitudinal section the ductile structures are viewed as ducts or tubules. That's why it got this name tubular pattern. The tubular lumen can be lined by one or more several layers of cells. So that is second pattern our tubular pattern whereas a third pattern solid pattern. tubular pattern is a group of cuboidal cells with little tendency towards ducts or cis formation. There is no ducts or cis formation. Instead it is arranged in nests or sheets of varying size and shape and you can see areas of necrosis between there is no tubular pattern it is necrosis may be seen. It is arranged in nests or sheets of varying size and shape and there are cellular pleomorphism and mitosis also observed. So that is solid pattern and now we have the treatment options and prognosis treatment mostly the surgical excision is opted and also associated along with x-ray radiation. Radiation alone is not recommended it is going hand in hand with surgery and cure it is basically low minor gland tumor is more deadlier than the major gland tumors so the palatal tumors will be more deadlier with less prognosis rate. So that's all about adenoid cystic carcinoma. So we have to learn carcinoma that is mucoepidoma and carcinoma. So similarly adenoid cystic carcinoma also important shot not it is frequently asked one. So these are the neoplasm malignant neoplasm which is seen in adenoid that is the salivary or the gland like structure. So we have seen adenoma toid or endogenic tumor the gland like so from the name we get this idea the gland cystic cyst formation in the glands and the carcinoma ok. So which is also known as cylindroma adenoid cystic carcinoma or adeno cystic basal cell carcinoma. So I will come up with another topic in the industry and more thank you.