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Published on Feb 18, 2014
Table of Contents: 00:09 Lecture 3.10: Cantilever-based Sensors Basic Operation 00:36 Outline 01:38 Three types of sensors 03:38 Mass of molecules 05:40 Why cantilever-based mechanical sensors 07:58 How does a cantilever sensor work 10:49 How to measure deflection 13:02 How to bring the biomolecule to the sensors 14:42 Outline 14:53 Equivalent spring-mass system 17:27 Equivalent spring-mass system 20:47 Oscillation in an ideal spring-mass 23:45 An Example 25:14 Mass only dynamic response: Ideal spring 27:04 Spring-only Dynamic response 28:54 Experimental Validation 29:17 Reversal of frequency at nanoscale 32:38 Composite effects and frequency reversal 34:12 Conclusions
This video is part of the nanoHUB-U course "Principles of Electronic Nanobiosensors".
This course provides an in-depth analysis of the origin of the extra-ordinary sensitivity, fundamental limits, and operating principles of modern nanobiosensors. The primary focus is the physics of biomolecule detection in terms of three elementary concepts: response time, sensitivity, and selectivity. And, it potentiometric, amperometric, and cantilever-based mass sensors to illustrate the application of these concepts to specific sensor technologies.