 Polysaccharide-based micelles are being used to improve the bioavailability of hydrophobic molecules and proteins by providing improved solubility and stability. Polysaccharides possess inherent bioactivity which can facilitate mucoadhesion, targeting of specific tissues and reduce inflammation. Additionally, their hydrophilic properties can increase circulatory stability. This article was authored by Nan Zhang, Patricia Orwardwell and Rebecca A. Bader.