 So, one of the more instructive processes that we've gone through in terms of partnerships this over this past couple of years has been UC-BRAID. And this is where we've tried to bring together the five UCs. You know, yes, we're all UCs, but no, we're not all UCSF. And so Rachel Seck has been, is our assistant director that's been responsible for this as well as some other programs. And she's going to give you all an overview of what the group is working on. And we wanted you all to see this because we think there's a lot more opportunity to do more with this organization. It also has lessons about the potential utility, too, of thinking about broader partnerships. So, Rachel? Thank you, Clay. Good morning, everybody. So, when I was just a quick intro, so when I was asked to give a brief presentation about UC-BRAID and this network, I was really excited and not because it was short and brief, but really because I think this is a great opportunity to raise awareness about this group's activities and efforts and actually to get people to start thinking and giving us feedback on how we can actually meet the potential of this group. So I'm going to be talking about UC-BRAID and what is UC-BRAID? So, BRAID stands for the University of California Biomedical Research Acceleration Integration and Development Consortium, and here too, for referred to as BRAID, is created about two years ago. And it's led by the principal investigators of the Affiliated Clinical and Translational Science Centers at the five biomedical campuses, so UC Davis, San Francisco, Los Angeles, Irvine, and San Diego. And so, why does BRAID exist? Well, it's been the conviction of the leadership and not just the BRAID leadership, the leadership across the campuses, deans and others, but there's issues across the campuses that are really better solved together than separately. And there's a recognition that there's shared policies. We work in an environment where there are some shared policies that we can work within and there's resources and complementary expertise across these campuses. And also that recognition that sometimes it just takes a force of will to get some of these difficult challenges moving forward. And in my less than one year working with BRAID, I can attest that that force of will is live and strong and moving forward. So, what does BRAID do? Well, the biggest thing is that what they're really trying to do is identify these shared challenges across the campuses and leverage the expertise at those campuses to work on the solutions for those issues and use the resources across those campuses as well. They ultimately are looking at developing system-wide solutions and knowing that those, these are can be policy changes, new infrastructure, or standardized processes. And how does it work? Well, the biggest thing is, BRAID doesn't and isn't a parallel organization. We aren't here to duplicate systems and governance and infrastructure. It's really all about working with the people across the campuses, bringing them together, the folks that actually conduct the work, the folks that actually conduct the policies and implement them. And the governance is really a conduit for the needs. It's taking the needs from the investigators, from the researchers, from the staff, and identifying them and helping prioritize them and then identifying the campus experts and the people that are in those areas across the campuses and bringing them together to work on those solutions and then enabling partnerships and trying to provide some little bit of administrative support as well to move these efforts forward. So, just to give you kind of a flavor of some of the initial areas where BRAID has been working, I thought I'd at least first touch upon UCREX, which stands for UC Research Exchange. And this is actually a full-fledged initiative that has funding from the Office of the President that's affiliated with BRAID. And they're actually, and I'll give you a quick description, they're actually creating the first-ever clinical cross-campus clinical data query system where you can actually query data at the patient level and aggregates as well. And again, this is a really large initiative. I think it's being led by Lucila Ono Machado at UC San Diego. And I think Latisse is in the audience, so she's the program lead there. If you have any questions about that, definitely go to Latisse. There's definitely some others I know in this room that work on this effort. In terms of, I'll touch upon a couple of these and you can always come to us if you have questions about the others. But in terms of contracting an IRB, this is really a group effort again, as I mentioned, across campuses working with the Office of the President as well, working on things like prioritizing and negotiating master clinical trials. The expansion of the memorandum of understanding for IRBs, and that's the IRB directors working very closely with the Office of the President in assisting them and expanding the memorandum of understanding to include high-risk clinical studies. And then, as you can see, a few of the other initiatives here that we've been working on. And then I should also mention, I mentioned there's funding for the UCREx initiative, but essentially the rest of the initiatives have been moving forward without any designated funding. It's really a lot of passionate people coming together and working together. However, we have recently put in a proposal to the Office of the President. We're hoping to hear from them within hopefully early next month to provide some seed funding to move forward the current initiatives that we're working on, but also some other initiatives that we're thinking about. I'll touch upon just a couple of these, the research corps sharing and the faculty research profiles. And so these would be initiatives, and again, these are proposed initiatives, where we'd be providing actually a cross-campus system-wide ways of searching intra and cross-campus for resources that are available, and also faculty expertise and researcher expertise. This really just a quick overview of all the various people that are really, really passionate and work really, really well together across the campuses and the Office of the President across these efforts. And thank you, I know a lot of you are in the room, so thank you to all of those for everybody's effort that do this, along with their day job. So it's been fantastic to actually see this in action. And I think with that, I'll leave it up to questions, and I'm going to ask Clay to come up as well to join because he's been helping me the helm on freight. Great. Thanks, Rachel. So, yeah, so again, one of the reasons we wanted you guys to see this is that it keeps coming up over and over again. You know, we identify problems that are at the UC level, or at the UCSF level, but could be addressed more effectively, more broadly at the UC level. And then people don't know that this entity exists, and they're surprised that they haven't heard about it. So we wanted to avoid that. I think, you know, there is real money here. So UCREX has got a $5 million grant. It's just in its first year, so a lot more should come from that. And that should cascade to a much more useful cross-UC platform for electronic health records. And then the proposal that we put in, I don't know if I should tell them because we don't know how much we'll get funded, but it's a $4 million proposal. It includes funding for some pretty ambitious projects that were identified by that group of names that you saw. And we hope we'll become a vehicle to collect ideas from the broader UC community that I'm like we do with our open forum now and select projects to move forward. So it really has a potential to grow quite a bit. So, questions, Janet? So the question I have is, I love profiles. And my understanding is that you are going to do profiles with Harvard first. Is it now going to be with all the UCs first? Well, do you want to answer? Sure, I could answer that. So UCS profiles has been a collaboration with Harvard and they're actually the developers of the system, right? And we implemented an instance here, here at UCSF, and then have actually grown and expanded upon that. And so what we showed here is a proposed project and actually initiative that would be quite large is to expand either profiles or something like that across the campuses so that you could do what you do right now. So you search for expertise and potential collaborators, but do it not only at UCSF and find those folks, but across the campuses. And they want to use profiles, actually. So at least three of the others want to use profiles. One's not quite sure yet. So that'll make it easier, but we want that search to occur regardless of what local platform they've got. But them using profiles, too, shows the value of doing this. So we can take, I shouldn't say how much we spend on profiles every year, but it's a lot. And it's going down, but it's a lot, that we can take their costs way down by supporting them through the infrastructure that we've already built. And then they can do that for us, for other projects. So it can dramatically reduce to upfront investment costs for things like profiles.