 This study compared two different approaches for treating trophic ulcers caused by venous insufficiency. One group received standard treatment including venotonics, compression bandages, and topical multi-component ointments. The other group received a combination of photodynamic therapy and a specialized wound dressing containing leviderm, a 5-aminolebulinic acid phosphate gel. Photodynamic therapy involves exposure to red light, which activates the skin's own natural photosensitizers and promotes faster healing. The results showed that the combination of photodynamic therapy and leviderm resulted in significantly shorter transition times to the second stage of wound healing and increased rates of epithelialization and granulation formation. These findings suggest that this combination may be effective in treating trophic ulcers caused by venous insufficiency. This article was authored by U.V. Venova, S.M. Gramituk, A. Krivarychko, and others. We are article.tv, links in the description below.