 Hopefully that will shift over, but in the meantime, so welcome back to a pretty packed schedule for the day. I thought we had a great introductory session last night that really set the frame for what we're interested in getting through today. One of the points that I wanted to make, there would be a redo. Actually while they're doing that, I might mention that this little camera here actually points at each of us and displays us, and so be careful when it's aiming at you. In addition, if you could take the green bags off of the table so we don't get any questions about why people are eating at a federal meeting, it would be very helpful. Excellent. So I don't actually have much to say in advance of the sessions today. I think everyone's already put in a lot of work into thinking about their presentations. One point that I did want to make though was just to clarify something that I don't think we fully clarified yesterday, and that may come up more in the discussions today, and that is particularly as we segue between the Mendelian space and the complex disease space. And that is that we can talk about something playing a causal role in a disease. In other words, it contributes in some mechanistic way to the onset of disease in that particular case, but of course that doesn't necessarily mean that it fully explains the disease in a particular patient. We had some examples yesterday over that. So I just want to make sure when we say causal here, we're not necessarily saying completely causal. We just mean contributes causally to that particular disease. So I think that's basically it from me. So I thought once Jeff's finished arguing with his neighbor, I think we can switch straight over to Jeff to start the first session of the day. Jeff will be discussing the work they've been doing and considering study design for assessing causality. And maybe I could just come in. Jeff, we'll have the timer set at 25 minutes for each of the presenters. So that's the amount that you'll get.