 Neural tube defects, NTDs, are serious congenital abnormalities that can lead to death or severe disability. Despite the best efforts to reduce their incidence through folate supplementation, they remain a major public health problem. In order to further reduce the number of NTDs, experts recommend that women who are at risk of having a baby with an NTD should consider interrupting their pregnancies before the 12th week of gestation. This decision must take into account both medical and religious values, as well as the woman's personal beliefs. By working together, doctors, nurses, and other health care professionals can provide support and guidance to women who need to make this difficult choice. This article was authored by Muhammad Fayyaz, Arshad Kashdel, and Shella Bakai.