 A retrospective study among Italian cancer health care workers found that influenza vaccination uptake gradually increased over three seasons, with the highest coverage in the 2020-21 season, particularly for health personnel. The study also revealed that males were more adherent to vaccination campaigns, but this gap decreased in the last season. Despite an increase in adherence due to the COVID-19 pandemic, further efforts are needed to achieve greater vaccination coverage among health care workers. This article was authored by Lucia Bertoni, Andrea Roncadori, Nicola Gentili, and others.