 This systematic review and meta-analysis found at Low Back Pain, LBP, has a significant clinical and economic burden in high-income countries, HICs. The estimated annual direct and indirect costs per population range from 2.3 billion euros to 2.6 billion euros, and the annual rate of hospitalization ranges from 3.2 percent to 5.7 percent. Additionally, the estimated direct costs and total costs per patient range from 9,231 U.S. dollars to 10,143 U.S. dollars. These findings suggest that LBP imposes a considerable financial burden on HICs, which could be reduced through targeted interventions such as prevention and management strategies. This article was authored by Francis Factoi, Francis Factoi, Tides Jebri, and others.