 This study used several non-invasive spectroscopic techniques to analyze the mural paintings in the Church of San Panfilo in Villa Grande di Torne in part, Italy. These techniques included digital optical microscopy, x-ray fluorescence spectroscopy, fiber optics reflectance spectroscopy, Fourier transform infrared spectroscopy, and Raman spectroscopy. Combining these techniques provided a comprehensive understanding of the painting's composition and enabled the identification of restoration areas. Additionally, the presence of modern compounds was identified, which was further confirmed through multiband imaging. This article was authored by Letizia Bonazzoni, Simone Callio, Anagalli, and others.