 Ocrotoxin A, OTA, is a mycotoxin produced by certain species of fungi, which can cause severe health issues in both animals and humans. It has been linked to various diseases such as poultry ocrotoxicosis, porcine nephropathy, and urinary tract tumors in humans. Despite decades of research, the exact mechanism of how OTA causes these diseases remains unclear. However, it is known that OTA is more toxic than other members of the ocrotoxin family, but it is not the only factor that contributes to the severity of the disease. Other factors such as the presence of other mycotoxins or their metabolites, combined with OTA, could also play a role in causing the disease. This article was authored by Alexandra H. Hussner and Louis E. H. Bingle.