 The UK Medical Research Council, MRC, recently launched the National Mouse Genetics Network, NMGN, a £22 million investment aimed at improving the translation of animal models into clinical applications. The NMGN will consist of seven challenge-led research clusters, each focusing on specific diseases or conditions and will provide access to genetically modified mice, data sharing, training, and specialised facilities. By integrating fundamental biological research with clinical findings, the NMGN hopes to improve the accuracy of animal models in predicting human disease.