 Hello, I'm Dr. Heidi Beednell and I'm a post-doctorate research fellow currently working at the Brain and Mind Centre at the University of Sydney. I'm really grateful to the Brain Foundation for supporting our research, looking at brain volume changes using MRI in patients from our clinic with relapsing multiple sclerosis. Overall, there's been a very high uptake of effective medication in this group of patients and subsequently there has been very limited clinical disease progression in most of them. And also we found that patients that appear to develop more MS lesions over time do seem to have higher rates of brain volume loss.