 The study evaluates whether TNF-alpha inhibitors cause changes in visceral adipose tissue, VAT, and if a calorie-restricted diet can prevent these changes in 20 patients with psoriasis. Results show that the combined treatment of TNF-alpha inhibitors and low-carbohydrates calorie-restricted diet significantly decreases body weight, BMI, waste circumference, trunk fat percentage, VAT, triglyceride levels, and total cholesterol levels compared to TNF-alpha inhibitors alone. The study concludes that the association between low-carbohydrates calorie-restricted diet and anti-TNF-alpha therapy improves the anthropometric profile of psoriasis patients. This article was authored by Campanati, Imolinelli, G-ganzetti, and others.