 Little has been published on the demographic composition of the Clinical and Translational Science Research Workforce within the Clinical and Translational Science Awards, CTSA, program despite the well-documented need for greater diversity in the biomedical research workforce. Analysis of workforce demographic reveal that women and members of underrepresented groups remain persistently underrepresented in the CTSA hub and training components principle investigators. In contrast, in the CTSA program career development and training programs, females have greater representation as participants and non-whites were better represented in training programs. This article was authored by Mercedes Rubio, Heather L. Baker and Jamie Nihoko Doyle.