 Chronic obstructive pulmonary disease, COPT, is a major public health concern in the Asia-Pacific region, with an estimated 10 million people affected. This study found that the presence of certain bacteria and viruses in sputum samples increases the risk of an exacerbation of COPT. Additionally, the presence of these pathogens decreases the quality of life of those suffering from COPT. This article was authored by Laura Tadi, Lucio Malvisi, David Eshui, and others.