 Hi everyone, I'm Annie from MIT. Today I would like to talk about an online searching platform for antibody resistance, their distribution in different bacteria species and global habitats. We first searched antibody resistant genes, the ARCs, in two datasets that are public available. The first one includes all the high quality bacteria genomes that covered more than 3,000 species, and all the plasmids and enterons. We also collected more than 850 managing arms from seven habitats, which includes some human-associated environments like animal faces, human faces, and wastewater treatment plants, and many natural environments. The published are our results on this online searching platform. You can visit this URL and search ARC, see how genomes and managing arms. For example, let's search ARCs in the bacteria species. Let's see. Bacteria fragilis. Here I'm using the default criteria. You can also change the identity and the value. Here are all the ARCs finding bacteriities. We can say there are ARCs resisting beta leptomes, tetracycline, and more tetracycline and sulfonamide. You can download the search results by this button. Using this tool, we made some interesting observations that more than 80% of ARCs are not carried by any plasmid or enteron that they're more likely to be non-mobile. We also find out the total abundance of ARCs is not significantly higher in humans-associated environments than nature environments. So we think it's important to differentiate ARCs of clinical relevance from ARCs that are non-mobile and common in nature environments. This paper is recently published on FEMS. You can check out more by this URL. And if you have more questions, please feel free to contact me through email. Thank you very much.