 This paper reviews various enhanced sampling techniques in molecular dynamic simulations, including collective variable biasing and tempering methods, offering historical and contemporary perspectives. The paper discusses mean force biasing using adaptive biasing force algorithm and temperature acceleration as well as bias potentials such as umbrella sampling and metodynamics. Additionally, parallel tempering and replica exchange methods are considered, concluding with a brief presentation of combination methods. This article was authored by Cameron Abrams and Giovanni Bussi.