 In this study, we examined the effects of dexmodetamidine on the myometrial contractions of pregnant rats. We found that dexmodetamidine had a dose-dependent effect on reducing the contractions of the myometrium, with the highest concentration causing complete suppression of contractions. Based on these results, it appears that clinically relevant concentrations of dexmodetamidine could be used safely in the obstetrical field. This article was authored by Dong Jun Kim, Young Jun Ki, Bo Hyun Jang and others.