 This qualitative research, conducted using a phenomenological approach, found that mental strains were the most important issues for COVID-19 patients, which were interwoven with concerning physical manifestations. Most participants used self-medication and spiritual resources to cope with the disease, so it is recommended that healthcare personnel plan to psychologically and spiritually support these patients while alleviating physical manifestations of the disease. This article was authored by Aliyah Scrooge-Azmi, Zahra Mohamed Zaydebrizi, Mostafa Rad, and others.