 In Italy, there are several pediatric oncohematological centers that provide care for children with cancer. These centers have different approaches when it comes to contact with animals, as some do not allow any contact at all while others allow limited contact under certain conditions. To address this issue, the Italian Association of Pediatric Hematology Oncology, AIPO, formed a working group consisting of infectious disease specialists, nurses, and veterinary experts. Together they drafted a consensus statement to outline the best practices for animal interactions in these centers. This statement provides guidelines for both clinical staff and families to ensure safety and reduce the risk of zoonotic diseases. This article was authored by Giulia Fumana, Debra Bata, Maria Francesca Dallaporta, and others.