 Thank you very much. It's such an honour to be here this evening to accept this generous research gift from the Brain Foundation. Our project concerns the role of vitamin D in neuro-inflammatory disorders. Autoimmune neuropathies occur when the nerves in the body, the insulation around these nerves become damaged, leading to progressive difficulties with movement and sensation. These disorders are costly in terms of healthcare costs and also in terms of burden on patients. However, we still do not fully understand the risk factors underlying the development of these disorders and we need to develop better markers of disease activity in order to direct appropriate treatment. Vitamin D is very important in modulating the immune system and reduced vitamin D levels are associated with autoimmune conditions such as multiple sclerosis and type 1 diabetes. Vitamin D is also known as vitamin sunshine and is associated with sun exposure and requires sun exposure to be produced. And so vitamin D levels are closely linked to a person's sun exposure levels and also their latitude or distance from the equator. Latitude is also associated with the prevalence of autoimmune disorders. So in Australia, multiple sclerosis is seven times more common in Tasmania, which is at a higher latitude than in Queensland with a lower latitude. Importantly, vitamin D levels have also been associated with disease severity and disability in MS patients. However, these factors have never been investigated in patients with autoimmune neuropathies. Our project will examine links between vitamin D and latitude in autoimmune neuropathies by looking at the rates of these disorders at different latitudes in Australia. In a group of patients, we will compare vitamin D levels with functional disability and compare to a cohort of MS patients. The overall aim of this research is to develop a marker of disease activity and to examine the potential for a trial of vitamin D supplementation in this patient cohort. And in fact, a world-first clinical trial of vitamin D supplementation in MS is currently being undertaken here in Australia. We're very excited to be starting this project here at the Brain and Mind Centre at the University of Sydney in conjunction with our colleagues in Physiology, the School of Public Health, Royal North Shore Hospital and the universities of Tasmania and Queensland. Thank you again to the Brain Foundation and all their supporters for this generous award that will enable us to conduct this research. Thank you.