 Monkeypox is a highly contagious virus that has been reported in over 75 countries worldwide. It poses a significant risk to global health due to its rapid spread and lack of effective treatment options. In order to prevent further spread of the virus, African nations must take immediate action to strengthen their healthcare systems and implement strategies to protect against future outbreaks. This includes developing vaccinations, improving surveillance and diagnostic capabilities, and increasing access to existing vaccines. Additionally, governments must work together to ensure that all citizens have access to adequate information about the virus and how to protect themselves. This article was authored by Emery Manurambona, Shuibu Saejimusa, Deborah Olawayza and Shomu Yua, and others.