 Non-melanoma skin cancer, NMSC, is a major health concern due to its high incidence rate and negative impact on quality of life, and surgery is not always applicable or available as primary treatment. Radiation therapy, RT, has shown to be an effective alternative or complementary method in cutaneous oncology, with favourable cosmetic results and excellent control rate of the tumour. Several techniques have been developed over the last 120 years, including radionuclide brachytherapy, electronic brachytherapy, x-ray therapies with KV to MV photons, and electron beam therapy. The article discusses these methods pros and cons in dematology practices and introduces a new approach of beta-RT for superficial skin tumours which may offer exciting features in the management of NMSC. This article was authored by Ali Poshizadeh, Axel Bose, and Michael Freeb.