This audio 'Adolescents living with HIV discuss the challenges, motivations and strategies for adherence' was produced for the online tool entitled 'Adolescent HIV testing, counselling and care: From guidance to action'. This tool provides guidance for health providers and planners and is designed to assist in the implementation of recommendations made in 'HIV and adolescents: Guidance for testing and counselling and care for adolescents living with HIV' issued by the World Health Organisation in 2013.