 mitochondria are one of the key organelles involved in cellular aging. As cells age, they accumulate defective mitochondria, leading to increased levels of mitochondrial oxidative stress. This oxidative stress can further damage the mitochondria, creating a vicious cycle that accelerates the aging process. To counteract this, researchers have proposed several strategies to reduce mitochondrial oxidative stress, including targeted drug therapies and lifestyle changes such as dietary supplements and exercise. These strategies could help slow down the progression of aging and age-related diseases. This article was authored by Yin Hengli, Myon UK Cooke, Moon Kyung-so, and others.