 Myokines and adipomyokines are proteins secreted from both skeletal muscles and adipose tissue. These proteins can have either inflammatory or anti-inflammatory effects depending on the amount present in the body at any given time. Myokines and adipomyokines also interact with each other as well as with other hormones and signaling pathways to influence metabolic processes such as glucose homeostasis and fatty acid oxidation. This article was authored by Siljarashki and Jurgen Echel.