 Good morning. I'm Dr. Seningar, Head of the Department of Medical Oncology at Center International Hospitals, Gurgaon. So today I'd like to discuss a few points about targeted therapy, which is a relatively new type of a cancer treatment, which is a part of personalized cancer medicine which is being followed all over the world for patients of advanced stages of cancer, stage 4 cancer patients in whom systemic therapy is the only option available for these kind of patients. Target therapy has emerged as a very good option and it is tailored based on the patient's genetics. The next generation's sequencing or the NGS report which is done on the tumour tissue helps us detect the genetic mutations for an individual patient and we have target therapies available against a lot of such genetic mutations and if we find some actionable genetic mutation then we can offer a targeted therapy against that. So this has helped us to tailor the cancer treatment in many types of cancer, predominantly lung cancer, breast cancer, and many other cancer types, colon cancer and it has proven to be a very life-changing type of a treatment modality, especially because it has lesser side effects if we compare with chemotherapy. So it is very good option in those patients of poor performance status in whom we cannot give chemotherapy completely. Also when it is combined with chemotherapy, the responses have shown to be, there has been an improvement in the disease-free survival and sometimes overall survival also in patients when combination with chemotherapy is done. So this is emerging as a very good treatment option and newer and newer target therapies are coming up for various cancer types and this obviously should be considered if someone is going through advanced cancer treatment. So this is a very good option to be considered. Thank you.